This is a common misconception used by some spa clinics to promote their cellular treatments while downplaying the limitations of their inexpensive administration methods. Mannitol, a diuretic, disrupts osmotic balance (osmoregulation) to facilitate the movement of soluble chemicals. However, it does not increase the permeability of the endothelial membrane, meaning it does not assist cellular material in crossing over into the brain (supposedly past the blood-brain barrier). If it did, blood cells could mix with cerebrospinal fluid, which is undesirable.

Disrupting osmoregulation systemically can lead to serious side effects, particularly in an already inflamed body, potentially impacting brain chemistry, renal function, nutritional bioavailability, electrolyte balance, heart function, and many other aspects of body chemistry that a patient may already be struggling to maintain.

Mannitol has been studied in pharmacology for its diuretic mechanisms that can help expand the reach of soluble drugs into the brain. While this advantage applies to chemical molecules designed to induce drug action within the brain, the systemic disturbance caused by mannitol can lead to a string of side effects. Therefore, it is crucial to consult with a physician to ensure that a patient’s body can cope with the secondary stresses induced by diuretic action.

Using a pharmaceutical product in unconventional ways can impact the body far beyond the scope or accountability of the therapeutic provider, which is not aligned with responsible healthcare practices. This reliance on unregulated methods is concerning. The side effects associated with the unconventional use of diuretics should be studied and understood by providers, and patients should be thoroughly informed.

Be safe and make choices based on what is right, not simply on what is being justified to you.